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Updated: Jun 26, 2025

The Use of Mouse Splenocytes to Assess Pathogen-associated Molecular Pattern Influence on Clock Gene Expression
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The Use of Mouse Splenocytes to Assess Pathogen-associated Molecular Pattern Influence on Clock Gene Expression

Published on: July 24, 2018

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循环时钟组件RORA通过抑制PD-L1表达增加了黑色素瘤中的免疫监测

Dandan Liu1,2, Benliang Wei3, Long Liang2

  • 1Department of Dermatology, Hunan Key Laboratory of Skin Cancer and Psoriasis, Hunan Engineering Research Center of Skin Health and Disease, Xiangya Clinical Research Center for Cancer Immunotherapy, Xiangya Hospital, Central South University, Changsha, China.

Cancer research
|May 8, 2024
PubMed
概括

与酸受体相关的孤儿受体-α (RORA) 抑制PD-L1,增强黑色素瘤的抗瘤免疫力. RORA表达式预测免疫疗法反应,提供了一个新的治疗点.

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