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Updated: Apr 12, 2026

Using Magnetometry to Monitor Cellular Incorporation and Subsequent Biodegradation of Chemically Synthetized Iron Oxide Nanoparticles
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在体内研究合剂修饰的纳米零价值铁:在小鼠中的生物分布和毒性

Minhui Hou1, Linwei Liu1, Yuqing Zhang1

  • 1Tianjin Key Laboratory of Environmental Technology for Complex Trans-Media Pollution, College of Environmental Science and Engineering, Nankai University, Tianjin, 300350, China.

Water research
|May 8, 2024
PubMed
概括

纳米级零价值铁 (nZVI) 主要分布到小鼠的肝脏和脏. 虽然通常是安全的,但nZVI可能会导致炎症和氧化应激,特别是在肝脏和脏.

关键词:
生物分布 生物分布化剂是一种化剂.我们的老鼠是老鼠.在纳米尺度零价值铁上.有毒性 有毒性

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Toxicity Testing in Animals01:23

Toxicity Testing in Animals

Toxicity tests in animals are grounded on two main assumptions: first, the effects observed in laboratory animals can be extrapolated to humans, especially when adjusted for body surface area; second, high-dose exposure in animals is essential to identify potential human hazards from lower doses. This is based on the quantal dose-response concept, which faces the challenge of extrapolating results from relatively few test animals to much larger human populations. For example, a 0.01% incidence...
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