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Updated: Jun 26, 2025

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在性结肠炎中,mTOR通过HIF1信号通路促进炎症反应

Yue Wang1, Ming Li2, AnSheng Zha3

  • 1Department of Gastroenterology, The First Affiliated Hospital of Anhui University of Chinese Medicine, Hefei 230031, People's Republic of China; Graduate School of Anhui University of Chinese Medicine, Hefei 230031, People's Republic of China.

International immunopharmacology
|May 8, 2024
PubMed
概括

拉巴胺素的哺乳动物标 (mTOR) 通过通过缺氧诱导因子-1α (HIF-1α) 途径促进T辅助者17 (Th17) 细胞分化,加剧性结肠炎 (UC) 炎症. 沉默mTOR可能会减少炎症,这表明mTOR抑制剂是潜在的UC治疗方法.

关键词:
在 HIF 信号通道上.炎症反应是一种炎症反应.性结肠炎是一种在mTOROR中使用mTOR.

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