篮子网状尺寸对部分填充 (500毫升) USP旋转篮子溶解试验液动力学的影响 装置 1

Chadakarn Sirasitthichoke1, Sanjaykumar Patel2, Kevin G Reuter3

  • 1Otto H. York Department of Chemical and Materials Engineering, New Jersey Institute of Technology, Newark, NJ 07102-1982, USA.

概括

粒子图像速度测量显示,美国药典 (USP) 旋转篮装置1中的不同网格大小显著改变了流体动力学和流速. 这影响了口服固体剂型的药物溶解概况.

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