对急性胆囊炎患者的扩展分析表明,结果因COVID-19状态和治疗方式而异
Emily A Grimsley1, Johnathan V Torikashvili1, Haroon M Janjua2
1Department of Surgery, University of South Florida Morsani College of Medicine, Tampa, Florida, United States.
概括
COVID-19感染阶段影响急性结石胆囊炎的结果. 胆囊切除术是COVID活跃和COVID康复患者的安全选择,提供与非手术治疗相似或更好的结果.
科学领域:
- 胃肠病学 胃肠病学
- 传染性疾病 传染性疾病
- 外科手术的结果
背景情况:
- COVID-19感染阶段对急性结石胆囊炎 (ACC) 结果的影响尚不清楚.
- 了解大流行期间的治疗影响对于患者管理至关重要.
研究的目的:
- 调查ACC结果,比较不同的治疗方式和COVID-19感染状态.
- 为了评估是否活跃的COVID-19感染恶化了ACC结果与康复或阴性患者相比.
主要方法:
- 利用了2020-2023年国家COVID队列成年ACC患者的协作数据.
- 分析了治疗方法 (抗生素,胆囊静脉切除术,胆囊切除术) 和COVID-19状态 (阴性,活跃,康复).
- 采用了通用线性模型来调整混因素并比较结果.
主要成果:
- 呈现出较高的败血症率的COVID活跃患者.
- 调整后的分析显示,胆囊切除术对COVID活跃和COVID阴性患者的死亡率较低.
- 在COVID阴性患者中,抗生素治疗失败更为常见.
结论:
- ACC的结果受到COVID-19阶段和治疗选择的影响.
- 胆囊切除术对于COVID活跃和COVID康复的患者来说是一个可行的和安全的选择.
- 非手术管理结果没有受到COVID-19恢复状态的负面影响.
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