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Updated: Jul 27, 2026

Molecular Profiling of the Invasive Tumor Microenvironment in a 3-Dimensional Model of Colorectal Cancer Cells and Ex vivo Fibroblasts
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综合单细胞分析破译了微环境动力学和免疫调节器 olfactomedin 4 在胆囊癌的发病过程中

Huisi He1,2, Shuzhen Chen3,2, Yong Yu4

  • 1National Center for Liver Cancer, Third Affiliated Hospital of Naval Medical University (Second Military Medical University), Shanghai, China.

Gut
|May 8, 2024
PubMed
概括

这项研究揭示了胆囊癌具有抑制免疫环境,并强调OLFM4是进展的关键驱动因素,提供潜在的治疗点.

关键词:
腺瘤腺瘤是一种胆囊癌是一种胆囊癌.这是一种炎症炎症炎症炎症.聚合物 (polyp) 是一种多重体.

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相关概念视频

The Tumor Microenvironment02:17

The Tumor Microenvironment

Every normal cell or tissue is embedded in a complex local environment called stroma, consisting of different cell types, a basal membrane, and blood vessels. As normal cells mutate and develop into cancer cells, their local environment also changes to allow cancer progression. The tumor microenvironment (TME) consists of a complex cellular matrix of stromal cells and the developing tumor. The cross-talk between cancer cells and surrounding stromal cells is critical to disrupt normal tissue...