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洞察寒冷透中的菌-细菌相互作用通过元基因组学和转录组分析,Gigantidas 平流体

Yan Zhang¹, Hao Chen¹, Chao Lian¹

¹Center of Deep Sea Research, and CAS Key Laboratory of Marine Ecology and Environmental Sciences, Institute of Oceanology, Chinese Academy of Sciences, Qingdao, 266071, China.

Scientific reports

|May 8, 2024

概括

分析了Gigantidas platifrons中的深海病毒,揭示了它们与甲类共生体的相互作用以及基于甲水平的不同社区结构. 这凸显了病毒在深海生态系统中的重要作用.

科学领域:

海洋微生物学海洋微生物学
深海生态深海生态
病毒学病毒学

背景情况:

病毒调节深海微生物群落和生物地化学循环,但它们在深海全生物体中的作用还未得到充分研究.
浴莫迪奥林海在它们的中宿主内共生细菌,以在冷时获得营养.
了解这些中的病毒群体对于深海生态系统动态至关重要.

研究的目的:

为了描述Gigantidas platifrons的病毒多样性和活动,来自南海寒冷透的贝.
研究病毒群落,甲度和贝类共生体之间的关系.
探索病毒在深海中所扮演的功能角色.

主要方法:

在鱼状组织中对病毒群体的元基因组和元转录组分析.
生物信息分析用于识别病毒家族,活跃病毒组和基因表达模式.
遗传学分析以确定病毒和宿主基因之间的进化关系.

主要成果:

确定了一个多样化的病毒群体,其中Caudovirales (Myoviridae,Siphoviridae,Podoviridae) 活跃表达.
病毒社区结构随着环境甲度的变化而显著变化.
在高甲环境中观察到病毒结构和复制基因的高表达.
两种特定的菌体表现出高表达和与甲性状共生体的相互作用,表达水平在甲度上有所不同.
证据表明,单链DNA病毒和病毒和共生生物之间共享基因 (Cro,DNA甲基酶) 的潜在作用.

结论:

这项研究揭示了Gigantidas platifrons贝中显著的病毒多样性和活性.
病毒群落受到甲度的影响,影响病毒与宿主相互作用.
病毒,特别是菌体,在贝和它们的甲性细菌之间的共生中发挥着动态作用.
这项研究为深海微生物在贝类全生物体内的相互作用提供了基础的见解.

关键词:

巨人巨人 (Gigantidas) 是一个平面巨人.甲基基因组是指甲基因组中的一部分.转录组转录组就是一个转录组.病毒病毒病毒病毒与主机的互动

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