需要为人类生殖系基因编辑设定明确目标的必要性 公共对话 公共对话
Wendy P Geuverink1,2, Diewertje Houtman3, Isabel R A Retel Helmrich3
1Department of Human Genetics, Amsterdam UMC, Location Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.
Journal of community genetics
|May 8, 2024
概括
确定公众和利益相关者参与 (PSE) 的明确目标对于对人类生殖基因编辑 (HGGE) 的有意义的审议至关重要. 本计划报告概述了吸引公众参与HGGE伦理和政策的四个基本目标.
科学领域:
- 生物伦理学生物伦理学
- 遗传技术对社会的影响
- 让公众参与科学活动
背景情况:
- 公众和利益相关者参与 (PSE) 对于解决人类生殖基因编辑 (HGGE) 的伦理和社会影响至关重要.
- 现有的PSE努力往往缺乏明确的目标,阻碍了有意义的对话和评估.
- 荷兰项目"De DNA dialogen" (DNA对话) 通过建立明确的参与目标来解决这一差距.
研究的目的:
- 概述荷兰"De DNA dialogen"项目关于公众和利益相关者参与HGGE的具体目标.
- 为有意义的PSE建立一个框架,使参与努力的评估成为可能.
- 在HGGE的背景下,为未来关于开放科学和治理的倡议提供信息.
主要方法:
- 跨学科项目联盟成员之间的商.
- 审查有关公众参与和HGGE的相关文献.
- 基于咨询和文献,制定了PSE的四个基本目标.
主要成果:
- 目标1:在讨论可行性 ("是否"和"如何") 之前,促进对假设的高度电流场景的审议.
- 目标2:研究价值和信念的共识/分歧,以便对HGGE进行精确的对话.
- 目标3:确保多样化和代表性不足的公众参与HGGE讨论.
- 目标4:通过揭示公众如何权衡与HGGE相关的价值观及其与民主原则的关系,为决策提供信息.
结论:
- 明确定义的目标对于有效和可评估的公众和利益相关者参与HGGE至关重要.
- 概述的目标为未来在敏感科学领域的PSE倡议提供了一个模型.
- 这种方法支持明智的政策制定,并在新兴遗传技术的背景下维护民主价值观.
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