与卡塔托尼亚和痴呆症相关的一般化周期性排放:一个案例系列
James Luccarelli1, Joshua R Smith1, Gregory Fricchione1
1Departments of Psychiatry (Luccarelli, Fricchione) and Neurology (Westover), Harvard Medical School, Boston; Department of Psychiatry, Massachusetts General Hospital, Boston (Luccarelli, Fricchione); Department of Psychiatry and Behavioral Sciences, Division of Child and Adolescent Psychiatry, Vanderbilt University Medical Center at Village of Vanderbilt, and Vanderbilt Kennedy Center, Vanderbilt University, Nashville, Tenn. (Smith); Department of Neurology, Beth Israel Deaconess Medical Center, Boston (Westover).
电脑电图 (EEG) 上的一般周期性放电可能表明了. 这项研究发现,患有一般性周期性泄漏和白内障的患者在使用二胺治疗后往往有所改善.
科学领域:
- 神经科学是一个神经科学.
- 临床神经学 临床神经学
- 在EEG分析分析.
背景情况:
- 一般化周期性放电 (GPD) 是一种与精神状态改变相关的EEG模式.
- 卡塔托尼是一种可治疗的神经精神疾病,具有特定的运动和行为症状.
研究的目的:
- 调查EEG和catatonia上一般周期性排放之间的关联.
- 为了评估患有GPDs的患者对catatonia的治疗反应.
主要方法:
- 使用布什 - 弗朗西斯白症评分表 (BFCRS) 诊断出白症的住院患者的回顾性病例系列分析.
- 分析包括患者与并发的EEG记录显示一般的周期性释放.
主要成果:
- 确定了五名患有白内障和脑电图GPD的患者.
- 五分之四的病人经历了显著改善的阴严重程度 (平均BFCRS减少6.75分) 后,二类药物治疗.
结论:
- 在适当的临床背景下,应考虑在患有一般性周期性排泄的患者中考虑catatonia.
- 对于患有同时发生的GPD和catatonia的患者来说,二类药物的实证试验可能是有益的.
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