创伤性脑损伤老年人中的冷漠和抑郁:与认知表现和心理社会功能之间的关系
Umesh M Venkatesan1, Amanda R Rabinowitz1
1Moss Rehabilitation Research Institute, Elkins Park, Pa.; Department of Rehabilitation Medicine, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia.
概括
在老年人中创伤性脑损伤 (TBI) 后的冷漠和抑郁是不同的情况. 区分它们是有针对性的干预措施的关键,以改善创伤后的生活质量和社会参与.
科学领域:
- 神经科学是一个神经科学.
- 老年学是一门学科.
- 精神病学是一个精神病学.
背景情况:
- 漠不关心和抑郁是中度到重度创伤性脑损伤 (TBI) 的普遍后果,特别影响老年人.
- 区分冷漠和抑郁是有效管理这一群体的关键.
研究的目的:
- 调查慢性TBI的老年人中冷漠和抑郁与认知功能之间的关系.
- 确定冷漠和抑郁对心理社会功能,包括与健康相关的生活质量 (HRQoL) 和社会参与的独特贡献.
主要方法:
- 106名老年人 (平均年龄64岁) 患有慢性中度至重度TBI,完成了对冷漠和抑郁的验证秤.
- 参与者接受了神经心理测试,评估了情节性记忆,处理速度和执行功能.
- 还评估了与健康有关的生活质量和社会参与.
主要成果:
- 漠不关心的严重程度与所有认知领域相关,特别是执行功能,即使在控制共变量之后.
- 抑郁症的严重程度没有显示出与认知表现的显著关联后纠正.
- 漠不关心和抑郁都独立影响HRQoL,而只有抑郁影响了社会参与.
- 临床冷漠和抑郁症的同时出现与较差的HRQoL和减少的社会参与有关.
结论:
- 这项研究是第一个将冷漠和抑郁症与老年TBI幸存者的认知和心理社会结果相关的研究.
- 研究结果强调了区分这些疾病的临床重要性,以便在这个脆弱人群中进行量身定制的精神和行为干预.
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