强迫性重复曲与屏住呼吸在缩大脑综合征
Jeremy D Schmahmann1, Wouter I Schievink1
1Ataxia Center (JDS), Cognitive Behavioral Neurology Unit, Laboratory for Neuroanatomy and Cerebellar Neurobiology, Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston; and Department of Neurosurgery (WIS), Cedars-Sinai Medical Center, Los Angeles, CA.
一个新的标志,强迫性重复屈曲与喘息 (CoRFBiS),是由自发性内低血压 (SIH) 引起的大脑松综合征 (SBS) 的病理标志. 这一发现有助于区分SBS和前性痴呆症.
科学领域:
- 神经学 神经学
- 神经成像是一种神经成像.
- 脑脊液动力学 脑脊液动力学
背景情况:
- 由于脑脊液 (CSF) 泄漏,自发的内低血压 (SIH) 可能导致头痛和脑综合征 (SBS).
- 包括神经认知缺陷在内的SBS症状可以模仿行为变异前性痴呆症 (bvFTD).
- 描述了一种新型的临床症状,可能是SBS的病理标志.
研究的目的:
- 为了识别和描述与脑综合征 (SBS) 相关的新临床症状.
- 为了确定SBS患者中这种征兆的患病率.
- 为了区分SBS和行为变体前性痴呆症 (bvFTD).
主要方法:
- 医疗记录和脑部成像的回顾性审查.
- 纳入标准:患有SIH,SBS和bvFTD类症状的患者.
- 评估特定的重复屈曲与喘息行为.
主要成果:
- 分析了51名患者 (平均年龄为55.5岁),他们在MRI上出现严重的脑部松.
- 18名患者 (35.3%) 表现出重复的曲与喘息 (CoRFBiS).
- 这种行为在临床表现时存在或在评估之前得到解决.
结论:
- 强迫性重复性曲与喘息 (CoRFBiS) 似乎是SBS的病理学标志.
- CoRFBiS可以作为SIH二次性SBS的重要临床指标.
- 对CoRFBiS的认可有助于区分SBS和bvFTD.
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