周产期物质使用障碍:检查对妊娠不良结果的影响
Alexandra S Ragsdale1, Noor Al-Hammadi2, Travis M Loux3
1Division of Maternal Fetal Medicine, Department of Obstetrics, Gynecology and Women's Health, Saint Louis University/SSM Health, St Louis, MO, USA.
患有物质使用障碍的孕妇面临着明显更高的不良妊娠结果风险. 关键风险包括胎儿生长限制,产前出血和早产,突出了严重的公共卫生问题.
科学领域:
- 产科和妇科 产科和妇科
- 公共卫生 公共卫生
- 成 药物 药物 药物 药物
背景情况:
- 药物使用障碍 (SUD) 在美国是一个越来越大的挑战,特别影响孕妇人口.
- 怀孕不良后果对母亲和婴儿的健康构成重大风险.
研究的目的:
- 评估物质使用障碍对不良妊娠结果的影响.
- 在全国范围的样本中确定受物质使用障碍影响的特定不良妊娠结果.
主要方法:
- 从医疗保健成本和利用项目国家住院患者样本对美国住院孕妇住院病人的横截面分析 (2016-2020年).
- 利用国际疾病分类 - 第10次修订代码来识别病例.
- 员工倾向得分匹配和多重物流回归用于分析.
主要成果:
- 使用SUD的怀孕住院患者的不良结果患病率较高 (35.6%) 与没有使用SUD的患者相比 (25.1%).
- SUD是不良妊娠结果的独立预测因子 (aOR 1.47,95% CI 1.45-1.49).
- 对于胎儿生长限制 (aOR 1.96),产前出血 (aOR 1.79) 和早产 (aOR 1.65) 观察到高风险.
结论:
- 药物使用障碍独立地与增加妊娠不良结果风险有关.
- 患有SUD的孕妇特别容易受到胎儿生长限制,产前出血和早产.
- 调查结果强调了有针对性的干预措施和对患有物质使用障碍的孕妇的支持的需要.
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