系统性红斑狼中的心血管发病率:单中心回顾性研究
Yousef Alammari1, Fahed A Albednah2, Khalid A Alharbi3
1Rheumatology, College of Medicine, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh, SAU.
Cureus
|May 9, 2024
概括
系统性红斑狼 (SLE) 患者经常出现心血管问题,如高血压. 然而,抗双链脱氧核糖核酸 (anti-dsDNA) 抗体可能会降低SLE患者的高血压风险.
科学领域:
- 类风湿病学 类风湿病学
- 心脏病学 心脏病学
- 免疫学 免疫学 免疫学
背景情况:
- 系统性红斑狼 (SLE) 是一种多系统的自身免疫性疾病.
- 心血管并发症影响约25%的SLE患者.
研究的目的:
- 为了确定国王法哈德医疗城 (KFMC) 的SLE患者心血管疾病的患病率.
- 确定常见的心血管并发症及其与SLE的关联.
主要方法:
- 从2015年1月到2023年10月,KFMC进行了基于记录的回顾性研究.
- 对所有SLE患者的医疗档案进行审查.
主要成果:
- 近一半 (45.2%) 的SLE患者患有心血管并发症.
- 高血压 (22.4%),膜心脏病 (13.2%) 和失脂症 (9.2%) 是最常见的.
- 反dsDNA抗体与高血压风险降低40%有关.
结论:
- 很大一部分SLE患者患有心血管并发症.
- 高血压,膜心脏病和脂质失调在SLE中很普遍.
- 反dsDNA抗体对SLE的高血压有保护作用.
相关概念视频
Assessment of the Cardiovascular System I: Subjective Data
320
A thorough health history and physical assessment are essential for identifying cardiovascular disease (CVD) symptoms and distinguishing them from other health issues.
Initial Enquiry
Ask the patient about their primary concern and thoroughly explore all reported symptoms.
Medical History
Investigate past illnesses affecting the cardiovascular system, such as angina, anemia, rheumatic fever, congenital heart disease, stroke, thrombophlebitis, dysrhythmias, varicosities
Inquire about symptoms...
Initial Enquiry
Ask the patient about their primary concern and thoroughly explore all reported symptoms.
Medical History
Investigate past illnesses affecting the cardiovascular system, such as angina, anemia, rheumatic fever, congenital heart disease, stroke, thrombophlebitis, dysrhythmias, varicosities
Inquire about symptoms...
320
Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers
80
Cardiac biomarkers are critical in diagnosing, prognosing, and managing cardiovascular diseases. Routine measurement of specific biomarkers such as B-type natriuretic peptide (BNP), C-reactive protein (CRP), and homocysteine (Hcy) is common practice in clinical settings to evaluate heart function and predict cardiovascular events.
These markers indicate stress or strain on the heart muscle:
Natriuretic Peptides (BNP)
Cardiac myocytes produce these hormones in response to ventricular stretching...
These markers indicate stress or strain on the heart muscle:
Natriuretic Peptides (BNP)
Cardiac myocytes produce these hormones in response to ventricular stretching...
80


