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Updated: Aug 1, 2026

Mechanical Stimulation-induced Calcium Wave Propagation in Cell Monolayers: The Example of Bovine Corneal Endothelial Cells
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赛马福林7A破坏了培养的人类角膜上皮细胞的屏障功能,这种方式取决于核因子-kappa B

Cheng-Cheng Yang1, Xiu-Xia Yang1, Xiao-Jing Zhao1

  • 1Department of Ophthalmology, the Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai 519000, Guangdong Province, China.

International journal of ophthalmology
|May 9, 2024
PubMed
概括

赛马福林7A (Sema7A) 通过通过NF-κB信号和IL-1β向下调节紧密结路来破坏角膜上皮质屏障功能. 抑制这些通路可能为角膜疾病提供治疗益处.

关键词:
屏障的功能是屏障的功能.人类角膜上皮质核因子-卡帕 B B 核因子奥克卢丁是什么? 奥克卢丁是什么穿越性皮质电阻的电阻区域封闭-1的区域.

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相关概念视频

NF-κB-dependent Signaling Pathway02:26

NF-κB-dependent Signaling Pathway

The transcription factor NF-κB was discovered in 1986 in the lab of Nobel laureate Professor David Baltimore, for its interaction with the immunoglobulin light chain enhancer in B-cells. After more than three decades of study, it is now evident that NF-κB regulates the expression of over 100 genes. Most of these genes play an essential role in the innate and adaptive immune responses as well as the inflammatory responses of animals.
NF-κB-dependent Signaling Mechanism
The heterodimer of NF-κB...