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对于超重或肥胖的人来说,补充
Gabriela Cormick1, Agustín Ciapponi2, Janetta Harbron3
1Instituto de Efectividad Clínica y Sanitaria (IECS-CONICET), Buenos Aires, Argentina.
补充剂对超重或肥胖个体的体重几乎没有影响. 然而,它可能会导致身体质量指数 (BMI) 和腰围的小幅降低,尽管证据的确定性很低.
科学领域:
- 营养与饮食学 营养与饮食学
- 肥胖问题研究研究
- 临床试验 临床试验
背景情况:
- 肥胖是一个全球性的健康问题,与许多慢性疾病有关.
- 越来越多的超重和肥胖在所有年龄组的流行.
- 摄入量与体重之间的潜在反向关系.
研究的目的:
- 评估补充剂对超重和肥胖个体减肥的影响.
- 评估在管理与肥胖有关的健康问题中的作用.
主要方法:
- 随机对照试验 (RCT) 的系统审查和元分析.
- 搜索了多个数据库,包括CENTRAL,MEDLINE,Embase和LILACS,直到2023年5月.
- 包括口服补充剂与安慰剂至少两个月内在超重/肥胖参与者的RCT.
主要成果:
- 包括1873名参与者的18项研究;所有这些都使用了口服补充剂.
- 低确定性证据表明体重差异很小或不存在 (MD -0.15公斤).
- 中等确定性证据表明,BMI (MD -0.18 kg/m2) 和腰围 (MD -0.51 cm) 的小幅减少.
结论:
- 补充可能会导致BMI和腰围的轻微减少,但证据的确定性低至中等.
- 没有观察到对体重的显著影响.
- 需要进一步研究对身体组成,特别是瘦身质量的影响.
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