在帕金森病中客观和主观执行功能之间的关系
Molly Split1, Celina Pluim McDowell2, Francesca V Lopez3
1Department of Psychological and Brain Sciences, Drexel University, Philadelphia, PA, USA.
概括
在帕金森病 (PD) 中,主观和客观的执行功能 (EF) 有关,尽管疲劳显著影响了对EF缺陷的自我意识. 了解这些差异是有效临床评估的关键.
科学领域:
- 神经科学是一个神经科学.
- 临床心理学 临床心理学
- 神经学 神经学
背景情况:
- 执行功能 (EF) 困难在帕金森病 (PD) 中很普遍.
- 在PD中主观自我报告EF (SEF) 和客观EF (OEF) 之间的相关性仍然不清楚.
- 澄清这种关系对于改善临床环境中的EF评估至关重要.
研究的目的:
- 在患有PD的个体中调查SEF和OEF之间的关系.
- 确定SEF和OEF之间的差异的预测因素.
- 探索与EF能力报告不足和过度报告相关的因素.
主要方法:
- 116名非痴呆PD参与者完成了OEF (解决问题,灵活性,抑制,工作记忆) 和SEF措施.
- 统计分析包括皮尔森相关性和线性回归.
- 探索性分析检查了报告不足,过度和准确的相关性.
主要成果:
- 在SEF投诉和更糟糕的OEF (β=.200,p=.009) 之间发现了显著的关联.
- 64%的参与者准确地报告了他们的OEF能力;28%报告不足,8%报告过多.
- 疲劳是EF差异最强的预测因素 (β=.281,p=.022),与教育,抑郁和焦虑一起.
结论:
- 主观和客观EF在PD中显著相关.
- 疲劳,抑郁,焦虑和教育水平会影响自我报告EF的准确性.
- 在PD的临床EF评估中,应考虑诸如疲劳和焦虑等非运动症状.
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