在初始门故障后,小儿眼中使用米托菌素-C进行第二次艾哈迈德眼植入的结果
Veronique Promelle1,2, Christopher J Lyons1
1Department of Ophthalmology and Visual Sciences, University of British Columbia, Vancouver, BC, Canada.
Journal of glaucoma
|May 9, 2024
概括
植入第二个艾哈迈德玻璃眼膜与mitomycin-C有效降低眼内压力和初始设备故障后儿童的药物需求. 这种手术为儿科绿眼管理提供了良好的中长期存活率.
科学领域:
- 眼科医生 眼科 眼科
- 玻璃眼的手术 玻璃眼的手术
- 儿科眼科医生 儿科眼科医生
背景情况:
- 青光眼排水装置 (GDD) 的长期有效性有限.
- 在儿科青光瘤中GDD失败后的最佳管理策略尚未得到充分确立.
研究的目的:
- 为了评估二次艾哈迈德大眼膜 (AGV) 植入与GDD失败后的儿童中mitomycin-C (MMC) 的结果.
主要方法:
- 在2000年至2019年期间接受了MMC的第二次AGV的儿科患者的回顾性图表审查.
- 通过眼内压力 (IOP) 定义的成功为5-21mmHg,有或没有药物,并且没有视力丧失.
主要成果:
- 分析了21名患者 (22只眼睛),显示IOP和药物需求的显著减少.
- 完全成功率在2年后为47%,在4年后为34%.
- 合格的成功率为2年后的74%,5年后的54%,严重并发症或视力丧失率为23%.
结论:
- 在儿童中使用MMC的二次AGV植入可以显著减少IOP和药物负担.
- 这种方法表明中长期的成功率与初级门植入相美.
- 存在显著的并发症风险,需要仔细考虑.
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