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Updated: Jun 26, 2025

Purification of the Membrane Compartment for Endoplasmic Reticulum-associated Degradation of Exogenous Antigens in Cross-presentation
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HERC3通过识别横跨膜的域来促进特定膜蛋白的ERAD

Yuka Kamada1, Yuko Ohnishi1, Chikako Nakashima1

  • 1Department of Biomedical Sciences, School of Biological and Environmental Sciences, Kwansei Gakuin University, Sanda, Japan.

The Journal of cell biology
|May 9, 2024
PubMed
概括

HERC3蛋白独特地针对错误折叠的CFTR通过ER相关降解 (ERAD) 降解,独立于RNF5/185. 这突出了HERC3的存在.

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