阻塞性睡眠呼吸暂停和心力衰竭的综合流行:系统性审查和元分析
Wisarud Prechaporn1, Phasu Hantrakul1, Chetta Ngamjarus2
1Department of Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.
Heart failure reviews
|May 9, 2024
概括
阻塞性睡眠呼吸暂停 (OSA) 在心力衰竭患者中很常见,综合患病率为38.4%. 心力衰竭也经常发生在OSA患者中,综合患病率为12.8%.
科学领域:
- 心脏病学 心脏病学
- 肺部病理学 肺部病理学
- 流行病学 流行病学
背景情况:
- 阻塞性睡眠呼吸暂停 (OSA) 的特点是睡眠期间间歇性低氧化.
- OSA和心力衰竭 (HF) 具有显著的双向关系,影响心血管健康.
- 了解HF患者中OSA的患病率和相反对于临床管理至关重要.
研究的目的:
- 为了估计被诊断为心力衰竭的患者中OSA的综合患病率.
- 为了确定在被诊断为OSA的患者中心力衰竭的综合患病率.
- 根据诊断标准和地理位置分析流行率的变化.
主要方法:
- 对观察性和流行病学研究进行系统审查和元分析.
- 搜索了四个数据库 (PubMed,Science Direct,Scopus,CINAHL Plus) 并进行了手动搜索.
- 利用比例元分析与随机效应模型来汇集流行数据.
主要成果:
- 在心力衰竭患者中,OSA的综合患病率为38.4% (95%CI为31.9至45.2).
- 使用诊断标准>10事件/小时,观察到较高的OSA患病率 (53.4%).
- 在OSA患者中,心力衰竭的综合患病率为12.8% (95%CI为8.1至19.5).
- 已注意到地理差异,印度的HF患病率中OSA患病率最高 (60.1%),罗马尼亚的OSA患病率中HF患病率最高 (22.6%).
结论:
- OSA在心力衰竭患者中非常普遍,心力衰竭也在OSA患者中很常见.
- 在心力衰竭患者中,OSA的综合患病率 (38.4%) 显著高于OSA患者 (12.8%) 的心力衰竭.
- 患病率受到OSA诊断标准和国家特定因素的影响.
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