印度急性肝衰竭的概述
1Kalinga Institute of Medical Sciences, KIIT University, Bhubaneswar, 751 024, India. subratacharya@gmail.com.
概括
急性肝衰竭 (ALF) 是一种严重的疾病,死亡率高. 早期预后模型,如ALF-Early Dynamic (ALFED) 模型,有助于选择肝移植患者,提高生存率.
科学领域:
- 肝病学 肝病学是一种肝病学.
- 关键护理医学 关键护理医学
- 移植手术 移植手术
背景情况:
- 急性肝衰竭 (ALF) 是急性肝损伤 (ALI) 的罕见但严重并发症,由各种原因引起,包括病毒,药物和代谢障碍.
- ALF表现为脑病变和凝血病,导致高死亡率 (50-80%) 和多个器官功能障碍.
- 并发症包括高血,脑,免疫,感染和细胞因子风暴,导致不良结果.
研究的目的:
- 审查急性肝衰竭 (ALF) 的病理生理学,并发症和治疗方法.
- 突出预后模型对及时干预,包括肝移植的重要性.
- 讨论ALF-早期动态 (ALFED) 模型在印度环境中的实用性.
主要方法:
- 关于急性肝衰竭 (ALF) 病因,临床表现和并发症的文献综述.
- 分析用于预测ALF死亡率的预后模型.
- 讨论治疗策略,包括医疗管理,器官支持和肝移植.
主要成果:
- 某些病因 (例如,肝炎E,A,) 和特定的治疗方法 (例如,N-乙半氨酸,抗病毒药物) 与更好的生存率有关.
- 大约50%的ALF患者可以通过医疗治疗和重症监护来挽救.
- 预后模型对于识别那些可以从早期肝移植中受益的患者至关重要.
结论:
- 密集护理和器官支持对于ALF患者的肝脏再生至关重要.
- ALF-Early Dynamic (ALFED) 模型是INASL推的,用于在印度早期选择ALF患者进行肝移植.
- 肝移植为精选的ALF患者提供了高的长期生存率.
更多相关视频
06:12Inducing Acute Liver Injury in Rats via Carbon Tetrachloride CCl4 Exposure Through an Orogastric Tube
Published on: April 28, 2020
11.3K
16:19Heterotopic Auxiliary Rat Liver Transplantation With Flow-regulated Portal Vein Arterialization in Acute Hepatic Failure
Published on: September 13, 2014
12.7K
相关概念视频
01:28Esophageal Varices-II: Clinical Features and Management
60
Esophageal varices often manifest as gastrointestinal bleeding episodes, presenting symptoms like hematemesis (vomiting of blood), hematochezia (passing fresh blood via the rectum), and melena (black, tarry stools). Other signs can include weight loss, anorexia, abdominal discomfort, jaundice, pruritus, altered mental status, and muscle cramps.
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol...
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol...
60
01:30Acute Pancreatitis II: Clinical Manifestations and Management
122
Acute pancreatitis presents a complex medical emergency characterized by rapid onset inflammation of the pancreas, demanding timely diagnosis and management to prevent complications. The condition primarily manifests through severe upper abdominal pain that often radiates to the back. This pain intensifies following the consumption of fatty foods. Accompanying symptoms such as nausea, vomiting, abdominal distention, fever, dyspnea, cyanosis, and jaundice can vary in intensity but significantly...
122
01:27Acute Pancreatitis I: Introduction
355
Pancreatitis is inflammation of the pancreas, an organ located behind the stomach. It can be either acute or chronic.
Acute pancreatitis is characterized by rapid inflammation of the pancreas, often caused by factors like gallstone blockage or excessive alcohol consumption. Chronic pancreatitis, on the other hand, is a slow, progressive inflammation that may result from long-term alcohol abuse, obstructions in the pancreatic duct, or genetic factors.
The causes of acute pancreatitis include:
Acute pancreatitis is characterized by rapid inflammation of the pancreas, often caused by factors like gallstone blockage or excessive alcohol consumption. Chronic pancreatitis, on the other hand, is a slow, progressive inflammation that may result from long-term alcohol abuse, obstructions in the pancreatic duct, or genetic factors.
The causes of acute pancreatitis include:
355
01:21Acute Respiratory Failure-I
202
Acute respiratory failure is a condition characterized by the inability of the lungs to perform their primary function: gas exchange. This failure leads to insufficient oxygen levels (hypoxemia) in the blood, elevated carbon dioxide levels (hypercapnia), or both, causing critical impairment in organ function.
Definition: It is defined by specific criteria based on blood gas measurements. Hypoxemia happens when the partial pressure of oxygen (PaO2) falls below 60 mmHg. At the same time,...
Definition: It is defined by specific criteria based on blood gas measurements. Hypoxemia happens when the partial pressure of oxygen (PaO2) falls below 60 mmHg. At the same time,...
202
01:26Diseases of the Liver and Gallbladder
527
Liver and gallbladder diseases are a significant health concern, with prominent conditions including cirrhosis, hepatitis, non-alcoholic fatty liver disease (NAFLD), and gallstones. Jaundice is a common manifestation of liver and biliary disease.
Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not...
Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not...
527
01:29Acute Respiratory Failure-V
135
The treatment for acute respiratory failure varies based on factors like the underlying cause, overall health, and severity. A collaborative healthcare team is essential for early detection, often through arterial blood gas analysis. Identifying the cause is the primary goal, with treatment strategies adjusted for ventilation/perfusion (V/Q) mismatch, shunting, or diffusion impairment.
Ensure that patients are monitored continuously for their response to therapy, including changes in...
Ensure that patients are monitored continuously for their response to therapy, including changes in...
135