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Updated: May 4, 2026

Potentiation of Anticancer Antibody Efficacy by Antineoplastic Drugs: Detection of Antibody-drug Synergism Using the Combination Index Equation
15:04

Potentiation of Anticancer Antibody Efficacy by Antineoplastic Drugs: Detection of Antibody-drug Synergism Using the Combination Index Equation

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剂量调整的EPOCH加伊诺图祖马布Ozogamicin在成人复发或耐火B细胞ALL:一期1剂量升级试验

Noam E Kopmar1,2, Kim Quach1,2, Ted A Gooley2

  • 1Division of Hematology-Oncology, Department of Medicine, University of Washington School of Medicine, Seattle.

JAMA oncology
|May 9, 2024
PubMed
概括

在剂量调整后的埃托波西德,普雷迪尼松,温克里斯,环胺和多克索鲁比辛 (DA-EPOCH) 化疗中添加伊诺图祖马布奥佐加米辛 (InO) 是对复发性或耐火性B细胞急性淋巴细胞白血病或淋巴瘤 (B-ALL) 的成年人可行和有效的治疗方法. 这种组合显示出高响应率和低发病率的阴侧阻塞综合征在一个严重预先治疗的人群.

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