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Updated: Jun 26, 2025

Preparation of Acute Brain Slices Using an Optimized N-Methyl-D-glucamine Protective Recovery Method
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对素2受体信号传输的动态和中间状态的结构和计算洞察力

Shun Yokoi1, Ryoji Suno2, Ayori Mitsutake1

  • 1Department of Physics, School of Science and Technology, Meiji University, 1-1-1 Higashi-Mita, Tama-ku, Kawasaki, Kanagawa 214-8571, Japan.

The journal of physical chemistry. B
|May 9, 2024
PubMed
概括

素2受体 (OX2R) 的激活涉及集体TM域运动,特别是TM3的垂直运动. 关键残留物Q134,V142和R152表现出显著的波动,影响OX2R药物发现的联结和信号选择性.

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