Alexander P Clark1, Trine Krogh-Madsen2,3, David J Christini1,4

  • 1Department of Biomedical Engineering, Cornell University, Ithaca, NY, USA.

PubMed
概括

人类诱导的多能干细胞衍生心肌细胞 (iPSC-CMs) 对药物测试有希望,但表现出显著的电生理学异质性. 这种由实验方法加剧的变异性阻碍了准确的患者特异性心血管疾病建模.

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