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Tao Zhang¹, Shiping Bai¹, Xuemei Ding¹

¹Key Laboratory of Animal Disease-Resistance Nutrition, Ministry of Education, Ministry of Agriculture and Rural Affairs, Key Laboratory of Sichuan Province, Animal Nutrition Institute, Sichuan Agricultural University, Chengdu, 611130, China.

Poultry science

|May 9, 2024

概括

棕素补充剂通过增强肠道功能,平衡肠道微生物群和减少炎症来改善产母的健康状况. 这种饮食补充剂还改善了脂质代谢和卵巢功能,可能会增加卵子的产量.

科学领域:

动物科学动物科学
营养生物化学营养生物化学
肠道微生物组研究研究

背景情况:

以调节人类和动物的脂质代谢和肠道微生物群而闻名的theabrownin在产母的研究是有限的.
了解abrownin的影响对于改善家禽健康和生产率至关重要.

研究的目的:

研究饮食中的茶素对产母的脂质代谢,肠道微生物群和卵巢功能的影响.
阐明棕素对肠道形态,炎症和肝脏脂质沉积的影响背后的机制.

主要方法:

80只母被分为一个对照组 (CON) 和一个棕色素补充组 (PT,100毫克/公斤) 12周.
评估了肠道形态,炎症性细胞因子表达,肝脂含量,与脂质代谢相关的肝基因表达,菌群组成,血清代谢物和卵巢功能标记物.

主要成果:

茶色素改善了肠道形态 (十二指甲状腺的高度,阴茎密室深度) 并减少了肠道炎症 (IL-1β,IL-6).
它降低了肝脏脂质沉积和改变了脂质代谢基因表达 (下调PPARγ,HMG-CoAS,ACC;上调CYP8B1).
棕色蛋白调节了卵巢微生物群,增加了有益的细菌 (Firmicutes,Lactobacillus) 和Firmicutes/Bacteroidetes比率,同时增强了卵巢功能 (Bcl-2,SIRT1表达,雌醇水平).

结论:

饮食中含有茶素可以增强肠道功能,调节肠道微生物群,减少产母的炎症.
棕素补充剂对脂质代谢和卵巢功能产生积极影响,可能通过SIRT1通路,有助于改善卵子体重和生产力.

关键词:

肠道微生物群;卵巢功能;产卵母的产卵母是什么意思代谢物的代谢物.他们在ABROWNIN.

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