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Updated: Jun 26, 2025

Studying the Effects of Tumor-Secreted Paracrine Ligands on Macrophage Activation using Co-Culture with Permeable Membrane Supports
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Studying the Effects of Tumor-Secreted Paracrine Ligands on Macrophage Activation using Co-Culture with Permeable Membrane Supports

Published on: November 28, 2019

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激活先天性免疫反应会使hPSC衍生的CAR巨细胞再极化,以改善抗瘤活性

Jun Shen1, Shuzhen Lyu1, Yingxi Xu1

  • 1State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Tianjin 300020, China.

Cell stem cell
|May 9, 2024
PubMed
概括

我们开发了一种高效的方法,可以从干细胞中产生化学抗原受体巨细胞 (CAR-Ms),用于癌症免疫治疗. 这些CAR-Ms通过免疫系统激活,在体外和体内显示出增强的瘤杀伤能力.

关键词:
人类多能干细胞干细胞免疫疗法 免疫疗法天生的适应性免疫系统.巨细胞是什么?巨细胞是什么?

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