在Helianthus annus中,TBBPA衍生物的吸收,生物转化和生理反应
Goujian Chi1, Hongxia Zhao1, Xiaonuo Zhang1
1Key Laboratory of Industrial Ecology and Environmental Engineering (Ministry of Education), School of Environmental Science and Technology, Dalian University of Technology, Dalian, 116024, China.
Chemosphere
|May 9, 2024
概括
年能有效吸收甲双二 (TBBPA BAE) 和甲双二二二 (TBBPA BDBPE),其中TBBPA BAE在植物中显示出更高的毒性和增长抑制.
科学领域:
- 环境科学 环境科学
- 植物科学 植物科学
- 毒理学 毒理学 毒理学
背景情况:
- 二甲 (TBBPA) 衍生物是广泛使用的制阻燃剂,其环境分布越来越多.
- 关于TBBPA衍生物的环境命运和植物相互作用的研究有限,需要进一步调查.
研究的目的:
- 为了研究TBBPA BAE和TBBPA BDBPE在Helianthus annus中的吸收,生物转化和生理反应.
- 了解植物处理这些TBBPA衍生物的机制,并评估它们的毒性.
主要方法:
- 使用暴露于TBBPA BAE和TBBPA BDBPE的Helianthus annus进行短期水培试验.
- 分析植物吸收,转移,生物转化 (代谢物识别) 和生理应激指标 (生长,MDA,抗氧化酶).
主要成果:
- 在第一级动力学之后,Helianthus annus对TBBPA BAE和TBBPA BDBPE都显示出高的去除效率 (>98%).
- TBBPA BAE被吸收和转移,而TBBPA BDBPE的转移受到疏水性限制. 确定了12种代谢物.
- TBBPA BAE抑制了生长并增加了MDA,表明毒性,而TBBPA BDBPE没有负面的生长影响. 两者都增加了抗氧化酶活性 (SOD,POD,CAT),TBBPA BAE显示了更高的诱导作用.
结论:
- 年可以有效地吸收和代谢TBBPA衍生物,对TBBPA BAE和TBBPA BDBPE有不同的行为.
- 与TBBPA BDBPE相比,TBBPA BAE对植物的毒理风险更高,其增长抑制和更强的抗氧化反应证明了这一点.
- 这项研究提高了对植物中TBBPA衍生生物转化的理解,这对于环境风险评估至关重要.
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