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永久右心室心脏起器植入后显著的副心脏反:预后影响
Takeru Nabeta1, Xavier Galloo1, Laurens Tops1
1Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands.
The American journal of cardiology
|May 9, 2024
概括
伴心 (MR) 影响近三分之一的患者在右心室 (RV) 心脏起器 (PM) 植入后. 这种情况独立预测不良心脏事件,包括死亡率和心力衰竭住院治疗.
科学领域:
- 心脏病学 心脏病学
- 心脏电生理学 心脏电生理学
- 心血管成像 - 心血管成像
背景情况:
- 在右心室 (RV) 心脏起器 (PM) 植入后,并未完全理解 mitra regurgitation (MR) 的发展.
- 在RV节奏之后,MR的预后影响需要进一步调查.
研究的目的:
- 为了确定 de novo RV PM 植入后显著的 MR 的流行率.
- 为了确定与PM后的MR发展相关的临床变量.
- 评估显著的MR和心脏结果之间的关联.
主要方法:
- 对451名患者进行了回顾性分析,这些患者接受了新的RV PM植入.
- 在基线和植入后评估MR患病率和严重程度.
- 多变量后勤和考克斯回归分析以确定预测因素和结果.
主要成果:
- 显著的MR (≥中度) 在29%的患者中发生,植入后平均为2.4年.
- 单腔PM,左心室末缩体积指数升高和基线轻度MR预测了显著的MR.
- 显著的MR独立地与不良心脏事件 (死亡率或心力衰竭住院) 相关.
结论:
- 大约三分之一的患者在RV PM植入后发展出显著的MR.
- 显著的MR是该人群中心脏不良事件的独立预测因素.
- 对PM后的MR机制和管理策略进行进一步的研究是有必要的.
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