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Updated: Jun 26, 2025

Assays for the Degradation of Misfolded Proteins in Cells
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Assays for the Degradation of Misfolded Proteins in Cells

Published on: August 28, 2016

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针对PRMT1的向蛋白质降解

Poppy L Martin1, Francisco Javier Pérez-Areales1, Shalini V Rao2

  • 1Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge, CB2 1EW, United Kingdom.

ChemMedChem
|May 9, 2024
PubMed
概括

在癌症治疗中,使用蛋白质分解向嵌合体 (PROTACs) 向蛋白质降解为向蛋白质氨酸甲基转移酶1 (PRMT1) 的直接抑制提供了潜在的优势.

关键词:
异生物功能的分子.在PRMT1中,这就是PROTAC.蛋白质阿基尼因甲基转移酶.有针对性的蛋白质降解.

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