Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Glial Cells01:04

Glial Cells

87.0K
Overview
87.0K
Nervous Tissue: Glial Cells01:31

Nervous Tissue: Glial Cells

2.9K
Glia, or neuroglia, are vital support cells that assist neurons in their functions. The term "glia" originates from the Greek word for "glue," reflecting their role in holding the nervous system together. These cells can be categorized into six types: four in the central nervous system (CNS) and two in the peripheral nervous system (PNS).
The CNS glial cell includes the astrocytes, the oligodendrocytes, the microglia, and the ependymal cells.
Astrocytes are star-shaped glial...
2.9K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Temozolomide Versus Radiotherapy as First-Line Therapy for Low-Grade Glioma: Mature Results of a Randomized Phase III Trial (EORTC 22033-26033/NCIC-CTG/TROG/MRC-CTU).

Journal of clinical oncology : official journal of the American Society of Clinical Oncology·2026
Same author

A prognostic human brain network for diffuse midline glioma.

Nature·2026
Same author

Prediction of treatment failure in patients with glioblastoma with perfusion MRI and molecular biomarkers.

Neuro-oncology advances·2026
Same author

Treatment Effect Reanalysis of the Randomized Individual Screening Trial of Innovative Glioblastoma Therapy in Newly Diagnosed Glioblastoma With External Control Data.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology·2026
Same author

cIMPACT-NOW update 12: Refining Pathology-based Risk Stratification and Grading for IDH-mutant Gliomas.

Neuro-oncology·2026
Same author

European neuro-oncology quality assessment (ENOQUA): A European organization for the research and treatment of cancer (EORTC) brain tumor group research project.

Neuro-oncology practice·2026
Same journal

Accidental hypothermia.

Nature reviews. Disease primers·2026
Same journal

Accidental hypothermia.

Nature reviews. Disease primers·2026
Same journal

Primary aldosteronism.

Nature reviews. Disease primers·2026
Same journal

Primary aldosteronism.

Nature reviews. Disease primers·2026
Same journal

Buruli ulcer in Africa: between innovation and pragmatism.

Nature reviews. Disease primers·2026
Same journal

Author Correction: Atopic dermatitis.

Nature reviews. Disease primers·2026
查看所有相关文章

相关实验视频

Updated: Jun 26, 2025

Author Spotlight: Enhanced Generation of Patient-Derived 3D Organoids for Glioblastoma and Glioma
05:45

Author Spotlight: Enhanced Generation of Patient-Derived 3D Organoids for Glioblastoma and Glioma

Published on: January 19, 2024

1.8K

质瘤是一种质瘤.

Michael Weller1, Patrick Y Wen2, Susan M Chang3

  • 1Department of Neurology & Brain Tumour Center, University Hospital Zurich & University of Zurich, Zurich, Switzerland. Michael.Weller@usz.ch.

Nature reviews. Disease primers
|May 9, 2024
PubMed
概括
此摘要是机器生成的。

脑瘤是源自神经干细胞的脑瘤,被世界卫生组织分为1-4级. 像IDH突变和IDH野生型质母细胞瘤这样的分子亚型定义了不同的预后和治疗策略.

更多相关视频

Isolation and Flow Cytometric Analysis of Glioma-infiltrating Peripheral Blood Mononuclear Cells
12:52

Isolation and Flow Cytometric Analysis of Glioma-infiltrating Peripheral Blood Mononuclear Cells

Published on: November 28, 2015

15.8K
Transposon Mediated Integration of Plasmid DNA into the Subventricular Zone of Neonatal Mice to Generate Novel Models of Glioblastoma
10:58

Transposon Mediated Integration of Plasmid DNA into the Subventricular Zone of Neonatal Mice to Generate Novel Models of Glioblastoma

Published on: February 22, 2015

12.9K

相关实验视频

Last Updated: Jun 26, 2025

Author Spotlight: Enhanced Generation of Patient-Derived 3D Organoids for Glioblastoma and Glioma
05:45

Author Spotlight: Enhanced Generation of Patient-Derived 3D Organoids for Glioblastoma and Glioma

Published on: January 19, 2024

1.8K
Isolation and Flow Cytometric Analysis of Glioma-infiltrating Peripheral Blood Mononuclear Cells
12:52

Isolation and Flow Cytometric Analysis of Glioma-infiltrating Peripheral Blood Mononuclear Cells

Published on: November 28, 2015

15.8K
Transposon Mediated Integration of Plasmid DNA into the Subventricular Zone of Neonatal Mice to Generate Novel Models of Glioblastoma
10:58

Transposon Mediated Integration of Plasmid DNA into the Subventricular Zone of Neonatal Mice to Generate Novel Models of Glioblastoma

Published on: February 22, 2015

12.9K

科学领域:

  • 神经瘤学神经瘤学
  • 癌症生物学 癌症生物学
  • 遗传学 是一个遗传学.

背景情况:

  • 质瘤是由基因改变的神经干细胞/原始细胞引起的原发性脑瘤.
  • 世卫组织的分类根据组织学和分子特征将质瘤分类为1-4等级.
  • 成人扩散性结质瘤包括IDH突变型/1p19q-codeleted oligodendrogliomas,IDH突变型星细胞瘤和IDH野生型结质瘤,每个都有独特的预后.

研究的目的:

  • 为提供质瘤分类和特征的概述.
  • 突出不同类型质瘤亚型的不同临床过程和结果.
  • 强调分子改变在指导治疗策略中的作用.

主要方法:

  • 审查当前世卫组织对中枢神经系统瘤的分类.
  • 对质瘤组织学和分子特征的分析.
  • 针对不同类型的质瘤亚型的临床结果和治疗反应的摘要.

主要成果:

  • 成人质瘤根据IDH突变和1p/19q代选择状态被分为三个主要类型,这决定了预后.
  • 儿科质瘤,如皮洛细胞性星瘤和扩散性中线质瘤,表现出不同的行为和结果.
  • 垂体瘤被分为生物学和预后上不同的亚型.
  • 针对主导信号通路的量身定制治疗改善了特定质瘤患者子组的结果.

结论:

  • 质瘤的分类依赖于综合的遗传病理学和分子数据.
  • 了解分子驱动因素对于预测预后和个性化治疗至关重要.
  • 分子诊断和向治疗的进步正在改善质瘤患者的治疗结果.