患有过敏性疾病的年轻成年人患开放角玻璃眼的风险:全国范围的队列研究
Kyungdo Han1, Jin-Hyung Jung2, Younhea Jung3
1Department of Statistics and Actuarial Science, Soongsil University, Seoul, Republic of Korea.
Scientific reports
|May 9, 2024
概括
喘,过敏性鼻炎和亚托皮炎等过敏性疾病与患初级开角玻璃眼的风险更高有关. 在这项大规模研究中,亚托邦性皮肤炎显示出最强的关联.
科学领域:
- 眼科医生 眼科 眼科
- 过敏学 过敏学
- 流行病学 流行病学
背景情况:
- 过敏性疾病是常见的慢性疾病.
- 主要的开角玻璃眼是不可逆转失明的主要原因.
- 过敏性疾病和青光眼之间的关系尚不清楚.
研究的目的:
- 研究过敏性疾病 (喘,过敏性鼻炎,亚托皮炎) 与初级开角玻璃眼的发病率之间的关联.
- 量化患有过敏症的个体中青光眼发育的风险.
主要方法:
- 利用了来自171,129名年龄在20-39岁之间的受试者 (2009-2015) 的韩国国家健康信息数据库 (KNHID) 数据.
- 采用Cox比例危险回归分析来评估青光眼风险.
- 根据潜在的混因素进行调整,包括性别,生活方式和并发症.
主要成果:
- 患有过敏性疾病的受试者患绿眼病的发病率更高.
- 对于至少有一种过敏性疾病的个体来说,眼的调整后危险比为1.39.
- 亚托皮炎 (aHR 1.73),过敏性鼻炎 (aHR 1.38) 和喘 (aHR 1.22) 都与增加的玻璃眼风险有关.
结论:
- 过敏性疾病显著与患初级开角绿内障的风险增加有关.
- 亚托匹性皮肤炎具有最高的风险,其次是过敏性鼻炎和喘.
- 调查结果强调了在格劳科马风险评估中考虑过敏状况的重要性.
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