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Updated: May 31, 2026

Analyzing Beneficial Effects of Nutritional Supplements on Intestinal Epithelial Barrier Functions During Experimental Colitis
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单细胞转录组分析显示,在检查点抑制性大肠炎中,免疫细胞对上皮质屏障功能障碍有明显的贡献

Molly Fisher Thomas1,2,3,4,5,6,7, Kamil Slowikowski8,9,10,11, Kasidet Manakongtreecheep12,13,14

  • 1Department of Medicine, Center for Immunology and Inflammatory Diseases, Massachusetts General Hospital, Boston, MA, USA. thomamol@ohsu.edu.

Nature medicine
|May 9, 2024
PubMed
概括

免疫检查点抑制性结肠炎 (irColitis) 的机制尚不清楚. 这项研究揭示了患者的特定T细胞扩张和上皮细胞变化,确定了IrColitis的潜在治疗点.

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