牙周炎是否与轻度认知障碍有任何关联?
Neeraj Gugnani1, Shalini Gugnani2
1Department of Pedodontics and Preventive Dentistry, DAV (C) Dental College Yamunanagar, Yamuna Nagar, Haryana, India. drgugnani@gmail.com.
Evidence-based dentistry
|May 9, 2024
概括
牙周炎显著增加患轻度认知障碍 (MCI) 的风险. 这种牙疾病是认知能力下降的显著危险因素,突显了口腔健康的重要性.
科学领域:
- 口腔健康和神经病学
- 系统性审查和元分析
背景情况:
- 轻度认知障碍 (MCI) 是一个日益严重的公共卫生问题.
- 牙周炎是一种常见的口腔感染,已被事地与全身健康问题联系起来.
研究的目的:
- 系统地审查和元分析牙周炎与轻度认知障碍之间的关联.
- 为了确定牙周炎是否是MCI的风险因素.
主要方法:
- 进行了观察性研究 (病例控制,队列,横截面) 的系统审查.
- 文献搜索包括PubMed,Scopus,Embase和Web of Science,并通过手动搜索来补充.
- 来自7项研究的数据被提取并使用固定效应模型进行分析,由于异质性较低.
主要成果:
- 分析显示,牙周炎和MCI之间存在显著的关联 (OR=1.70).
- 严重的牙周炎与MCI的相关性更强 (OR = 2.09).
- 在患有MCI的患者中,牙周的参数,如临床附着损失 (CAL) 和斑块指数 (PI) 显著恶化.
结论:
- 牙周炎是发展轻度认知障碍的重要危险因素.
- 调查结果强调了口腔健康的系统性影响和综合医疗保健方法的必要性.
相关概念视频
Alzheimer's Disease: Overview
467
Alzheimer's Disease (AD) is a continually advancing neurodegenerative disorder, distinguished by escalating memory loss, cognitive dysfunction, and dementia. The disease unfolds in three stages: preclinical, mild cognitive impairment (MCI), and dementia. Its onset is insidious, and the progression gradual, with the cause not well explained by other disorders.
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ...
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ...
467
Dementia
112
Dementia is a collective term for cognitive disorders primarily affecting memory, thinking, and reasoning. It is not a specific disease but a syndrome, with Alzheimer's disease being the most common cause, accounting for approximately 60-80% of cases. Other types include vascular dementia, Lewy body dementia, and frontotemporal dementia. Dementia affects millions worldwide, particularly older adults, though it is not a normal part of aging.
The progression of dementia is generally gradual....
The progression of dementia is generally gradual....
112
Teeth
394
The formation of teeth, also known as odontogenesis, is a complex process that begins in utero, around the sixth week of embryonic development. There are three stages to this process: the bud stage, the cap stage, and the bell stage.
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin...
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin...
394


