口服处方管理的管理方法
1Drexel University College of Medicine, Philadelphia, PA, USA. ass333@drexel.edu.
Advances in experimental medicine and biology
|May 9, 2024
概括
针对阿托皮性皮炎 (AD) 的新口服治疗方法提供更快的缓解和更少的副作用. 简氏激酶 (JAK) 抑制剂显示出有希望的结果,但由于潜在的风险,需要对患者进行谨慎的选择.
科学领域:
- 皮肤病学 皮肤病学
- 药理学 药理学是指药理学的学科.
背景情况:
- 口服治疗阿托皮性皮肤炎 (AD) 历史上因副作用而面临限制.
- 长期使用口服皮质类固醇和免疫抑制剂治疗阿尔茨海默病的爆发受到副作用和监测需求的限制.
研究的目的:
- 审查目前和新兴的阿托皮性皮肤炎口服治疗选择.
- 评估新的全身疗法的安全性和疗效,包括Janus激酶 (JAK) 抑制剂.
主要方法:
- 对阿托皮性皮肤炎的现有和新型口服疗法的文献综述.
- 对安全数据的分析,包括JAK抑制剂的黑子警告.
- 讨论抗生素和抗组胺剂在阿尔茨海默病管理中的作用.
主要成果:
- 类激酶 (JAK) 抑制剂是阿尔茨海默病的有希望的新选择,因为它们的迅速发作和抗作用.
- 尽管在试验中最初的安全性很好,但JAK抑制剂带有黑子警告,需要仔细选择和教育患者.
- 像皮质类固醇和免疫抑制剂这样的传统药物长期效用有限.
结论:
- 新兴的口服疗法,特别是JAK抑制剂,为亚托皮炎管理提供了新的途径.
- 风险效益评估和患者教育对于新型系统性药物的安全有效使用至关重要.
- 对各种口服药物的全面了解对于优化AD治疗策略至关重要.
相关概念视频
01:02Prescription, Nonprescription and Orphan Drugs
721
Prescription drugs require a prescription from a medical practitioner and can only be obtained from a pharmacy. They have many applications, including treating pain, anxiety, and hypertension.
The misuse and addiction to prescription drugs is a growing problem that can affect people of all age groups, specifically teenagers. This can happen when prescription medications are used in ways not intended by the prescriber, such as taking someone else's prescription or using medication for...
The misuse and addiction to prescription drugs is a growing problem that can affect people of all age groups, specifically teenagers. This can happen when prescription medications are used in ways not intended by the prescriber, such as taking someone else's prescription or using medication for...
721
01:22Drug Delivery: Miscellaneous Routes
338
Drug delivery methods like oral inhalation, nasal sprays, transdermal patches, eye drops, intravitreal injection, and rectal administration provide localized effects with reduced toxicity.
Oral inhalation and nasal sprays swiftly transfer drugs across the respiratory epithelium's mucosal layer. Inhaled glucocorticoids and bronchodilators directly target lung conditions such as asthma, while fluticasone nasal spray mitigates allergic rhinitis.
Transdermal patches transport drugs...
Oral inhalation and nasal sprays swiftly transfer drugs across the respiratory epithelium's mucosal layer. Inhaled glucocorticoids and bronchodilators directly target lung conditions such as asthma, while fluticasone nasal spray mitigates allergic rhinitis.
Transdermal patches transport drugs...
338
01:18Drug Delivery: Enteral Route
422
The enteral drug administration involves three primary routes: oral, sublingual, and buccal. Oral ingestion is the most prevalent, safe, economical, and convenient method for drug administration. However, it has certain drawbacks, including limited absorption due to the drug's low water solubility or poor membrane permeability, possible emesis from GI mucosa irritation, destruction of drugs by digestive enzymes or low gastric pH, and irregular absorption along with food or other drugs.
422
01:28Drug Therapy
42
The advent of drug therapy has profoundly shaped modern mental health care, providing targeted treatments for a range of psychological disorders. Psychotherapeutic drugs, classified into antianxiety, antidepressant, and antipsychotic medications, address symptoms across anxiety disorders, mood disorders, and schizophrenia. While these medications have transformed patient outcomes, they require careful management due to their potential side effects and limitations.
Antianxiety Medications
Antianxiety Medications
42
01:23Inhaled Medications
252
Inhaled medications are crucial for managing chronic obstructive pulmonary disease (COPD) and asthma. They are essential for effective treatment and control, ensuring optimal respiratory health and well-being. Inhaled medication delivers drugs directly to the lungs, providing a rapid onset of action and reducing systemic side effects compared to oral or injectable medications. Three primary types of inhalation devices are used to administer these medications: nebulizers, metered-dose inhalers...
252
01:18Additional Routes of Drug Administration
2.7K
Choosing the appropriate route of drug administration is significantly influenced by two key factors: the therapeutic objectives and the inherent properties of the drug being used.
Administering drugs via inhalation allows for the direct delivery of gaseous, volatile substances or droplets to different parts of the respiratory tract. One of the advantages of the inhalation route is the rapid absorption of drugs into the circulatory system, which is possible because of the large surface area of...
Administering drugs via inhalation allows for the direct delivery of gaseous, volatile substances or droplets to different parts of the respiratory tract. One of the advantages of the inhalation route is the rapid absorption of drugs into the circulatory system, which is possible because of the large surface area of...
2.7K