骨菌株在运行时对速度扰动敏感,但对等级扰动敏感,而不是等级扰动
Michael Baggaley1,2, Ifaz Haider1,2, Olivia Bruce1,2,3
1Faculty of Kinesiology, University of Calgary, 2500 University Dr. NW, Calgary, AB, Canada, T2N 1N4.
The Journal of experimental biology
|May 10, 2024
概括
跑得更快会显著增加骨应变和骨损伤风险,可能导致压力骨折. 跑步度的变化 (倾斜/下降) 对骨应变没有显著影响.
科学领域:
- 生物力学 生物力学
- 整形外科 整形外科 整形外科
- 运动医学 运动医学
背景情况:
- 骨压力骨折通常与疲劳失败有关,骨损伤受到峰值应变的影响.
- 之前关于跑步诱导的小腿应变的研究基本上忽视了不同地形等级的影响.
研究的目的:
- 为了研究如何改变运行等级和速度会影响骨应变.
- 为了确定上坡和下坡跑步与平面跑步相比是否会改变部应变.
主要方法:
- 使用肌肉骨有限元素建模方法.
- 收集了17名参与者在跑步机上以各种等级 (±10°,±5°,0°) 和速度运行的运动和力数据.
- 估计的肌肉和关节力量应用于骨的个性化有限元素模型.
主要成果:
- 肌张力变量 (峰值张力,张力体积) 并没有受到运行等级的显著影响.
- 所有测量的小腿骨应变量都对跑步速度表现出显著的敏感性.
- 运行速度增加1米/秒导致峰值应变增加9%,应变体积增加155%.
结论:
- 更快的跑步速度似乎比跑步等级的变化对骨更有害.
- 跑步速度是影响骨应变和压力骨折发展潜力的关键因素.
相关概念视频
Defense Against Bacterial Pathogens
3.1K
The human immune system is a complex network of cells, tissues, and organs that work together to defend the body against bacterial infections. It consists of various immune cells, each playing a specific role in the defense mechanism.
Phagocytes
Phagocytes are the frontline soldiers of the immune system. They include neutrophils and macrophages. Neutrophils are the most abundant type of white blood cell and are quickly mobilized to the site of infection. Macrophages are larger cells that patrol...
Phagocytes
Phagocytes are the frontline soldiers of the immune system. They include neutrophils and macrophages. Neutrophils are the most abundant type of white blood cell and are quickly mobilized to the site of infection. Macrophages are larger cells that patrol...
3.1K
Factors Influencing Microbial Growth: pH
1.9K
Microorganisms are classified as acidophiles, neutrophiles, or alkaliphiles based on their pH growth preferences, reflecting their adaptations to specific environments. Maintaining a stable intracellular pH is critical for macromolecular stability and enzymatic activity, which can be challenged by external pH variations.Neutrophiles, such as Escherichia coli, grow optimally between pH 5.5 and 8.0. These microorganisms inhabit neutral or slightly acidic environments and employ mechanisms like...
1.9K
Stringent Response in E. coli
533
Bacterial growth is closely tied to nutrient availability, with cells proliferating exponentially under favorable conditions and entering a stationary phase when resources become scarce. This transition is mediated by a regulatory mechanism known as the stringent response, which allows bacteria to adapt to nutrient deprivation by modulating gene expression and metabolic activity.During nutrient scarcity, intracellular amino acid levels decline. It results in the accumulation of uncharged tRNAs...
533
Other Stress Responses in Bacteria
593
Bacteria have global regulatory systems that control several types of stress mechanisms. These include Pho regulon and the heat shock response, which are essential systems for environmental adaptation, such as nutrient limitation and proteotoxic stress. The Pho regulon and the heat shock response exemplify bacterial resilience, enabling rapid adaptation to fluctuating environmental conditions.Pho RegulonBacteria require phosphorus for essential cellular processes, including nucleic acid...
593


