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Updated: Jun 26, 2025

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TAZ缺乏会通过NRF2失调和溶酶体功能障碍损害自-溶酶体通路

Hyo Kyeong Kim1, Hana Jeong1, Mi Gyeong Jeong1

  • 1College of Pharmacy and Graduate School of Pharmaceutical Sciences, Ewha Womans University, Seoul 03760, Korea.

International journal of biological sciences
|May 10, 2024
PubMed
概括

具有PDZ结合基因 (TAZ) 的转录协活性剂调节核因素红色素2相关因子2 (NRF2) 信号传递. TAZ 缺乏会损害NRF2介导的自-溶酶体通路,从而导致氧化应激导致的肺损伤.

关键词:
这就是NRF2的NRF2.塔兹塔兹是什么意思?塔兹塔兹是什么意思自自是自的过程.lysosomal 酸性化发生的情况.氧化应激是一种氧化应激.

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