计划进行关节或膝关节置换的患者的精神药物治疗
Simon Kornvig1,2, Henrik Kehlet3,4, Christoffer Calov Jørgensen3,4,5
1Department of Orthopaedic Surgery, Lillebaelt Hospital - Vejle, Vejle, Denmark.
Basic & clinical pharmacology & toxicology
|May 10, 2024
概括
精神药物治疗,特别是抗抑郁药,如SSRI和SNRIs,在关节和膝关节置换患者中很常见. 在手术周围暂时停止服用这些药物可能是可行的和有益的.
科学领域:
- 整形外科手术 整形外科手术
- 心理药理学 心理药理学
- 患者的治疗结果.
背景情况:
- 精神药物治疗可能会增加关节和膝关节置换手术后的住院和再入院率.
- 在外科手术期间暂停这些药物的可行性尚不清楚.
研究的目的:
- 在接受关节或膝关节置换的患者中描述心理药物治疗.
- 评估暂时暂停这些治疗的可行性.
主要方法:
- 在2021-2023年间对482名接受关节或膝关节置换的患者进行了回顾性研究.
- 分析药物类型,剂量,持续时间,适用情况和处方医生.
主要成果:
- 89%的患者使用抗抑郁药,最常见的是SSRI (48%) 和SNRIs (21%).
- 70%的人接受单疗法,主要是SSRI (36%) 或SNRIs (12%).
- 大多数抗抑郁药是由全科医生发起的,通常用于抑郁症 (77%),并且持续了一年多.
结论:
- 在关节和膝关节置换患者中,暂时停止SSRI/SNRIs似乎是可行的.
- 需要进一步的研究,包括随机对照试验,以调查暂时停止治疗的益处.
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