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红斑狼皮肤表现的系统相关性
Peter M Heil1,2, Mark R Pittelkow3, Amy L Weaver4
1Department of Dermatology, Medical University of Vienna, Vienna, Austria.
International journal of dermatology
|May 10, 2024
概括
系统性红斑狼 (SLE) 患者的皮肤疾病很常见. 红斑狼 (LE) 皮肤病的存在没有影响SLE的严重程度,爆发,药物或存活率.
科学领域:
- 皮肤病学 皮肤病学
- 类风湿病学 类风湿病学
- 免疫学 免疫学 免疫学
背景情况:
- 系统性红斑狼 (SLE) 经常表现为皮肤表现.
- 了解红斑狼 (LE) 皮肤病的流行率和相关性对于全面的患者管理至关重要.
研究的目的:
- 为了确定SLE患者皮肤疾病的患病率.
- 为了确定LE皮肤病与SLE的临床和血清学关联.
主要方法:
- 对335名SLE患者的医疗记录进行了回顾性审查.
- 抽象数据包括皮肤表现,粘膜皮肤SLE标准和临床/血清学参数.
主要成果:
- 在231名患有皮肤问题的患者中,24.7%患有LE特异性,44.2%患有LE非特异性,31.2%患有两种情况.
- 与光敏感性,抗史密斯和抗U1RNP抗体相关的LE皮肤病 (P < 0.001).
- 没有LE皮肤病与高C反应蛋白 (P=0.01) 有关.
结论:
- 乐氏体皮肤病是SLE患者经常出现的并发症.
- 患有LE皮肤病的存在与增加的SLE严重程度,爆发,药物使用或减少的存活率无关.
- LE皮肤病没有影响系统性SLE后果.
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