2020年COVID-19大流行期间的癌症发病率,阶段转变和生存率:比利时的一项基于人口的研究
Hanna M Peacock1, Mira Van Meensel1, Bart Van Gool1
1Belgian Cancer Registry, Brussels, Belgium.
International journal of cancer
|May 10, 2024
概括
2020年,COVID-19大流行导致比利时的癌症诊断减少了5000多例. 这导致诊断延迟,影响了几种常见癌症的癌症阶段和存活率.
科学领域:
- 在瘤学瘤学.
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 在全球范围内,COVID-19大流行严重扰乱了医疗保健服务.
- 这种破坏引起了人们对其对癌症诊断,分期和患者结果的影响的担忧.
- 比利时在2020年经历了癌症诊断的显著下降.
研究的目的:
- 量化COVID-19大流行对2020年比利时癌症发病率,阶段分布和生存率的影响.
- 将2020年观察到的癌症数据与基于大流行前趋势的预测进行比较.
- 分析11种常见癌症类型的变化.
主要方法:
- 利用了所有比利时的强制性癌症登记数据.
- 采用波桑计数模型来预测2020年的癌症发病率,阶段和1年相对存活率.
- 将预测值与观察到的2020年数据进行比较,并考虑背景趋势.
主要成果:
- 观察到宫癌,前列腺癌,头癌,结肠直肠癌,膀癌和乳腺癌的发病率明显降低.
- 在2020年下半年,这些癌症的诊断显示出有限的恢复.
- 宫癌,前列腺癌,膀癌,卵巢癌和输卵管癌的阶段分布发生了变化,早期诊断下降.
- 一年相对存活率低于肺癌和结直肠癌的预测.
- 到2020年底,癌症诊断的数量比预期少了5000多例.
结论:
- 2020年,COVID-19大流行导致比利时的癌症诊断大幅减少.
- 观察到阶段转移,可能是由于诊断访问问题和患者的犹.
- 持续监测癌症发病率,癌症阶段和癌症存活率在后疫情时代至关重要.
更多相关视频
06:46Competing-Risk Nomogram for Predicting Cancer-Specific Survival in Multiple Primary Colorectal Cancer Patients after Surgery
Published on: September 27, 2024
256
13:19Quantifying Antibody-Dependent Cellular Cytotoxicity in a Tumor Spheroid Model: Application for Drug Discovery
Published on: April 26, 2024
2.6K
相关概念视频
01:21Cancer Survival Analysis
345
Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
345
01:30Cancer Vaccines
358
Cancer treatment vaccines are a rapidly evolving field that offers a promising approach to immunotherapy. Unlike traditional vaccines that prevent diseases, cancer treatment vaccines are designed to treat existing cancers by stimulating the immune system to recognize and attack cancer cells.
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
358
02:07Tumor Progression
6.3K
Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
6.3K
02:12What is Cancer?
10.7K
Cells and tissues must meticulously coordinate their activities for the normal functioning of the human body. Therefore, they exhibit socially responsible behavior - resting, growing, dividing, differentiating, or dying - for the organism’s benefit. Cancer arises when cells divide uncontrollably and invade other tissues or organs.
Although people have known about cancer for centuries, it was only in 1761 that Giovanni Morgagni of Padua performed a detailed autopsy of...
Although people have known about cancer for centuries, it was only in 1761 that Giovanni Morgagni of Padua performed a detailed autopsy of...
10.7K
02:49Cancer Therapies
7.6K
Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
7.6K
01:33Cancer-Critical Genes I: Proto-oncogenes
8.8K
Genes usually encode proteins necessary for the proper functioning of a healthy cell. Mutations can often cause changes to the gene expression pattern, thereby altering the phenotype.
When the function of certain critical genes, especially those involved in cell cycle regulation and cell growth signaling cascades, gets disrupted, it upsets the cell cycle progression. Such cells with unchecked cell cycles start proliferating uncontrollably and eventually develop into tumors.
Such genes that act...
When the function of certain critical genes, especially those involved in cell cycle regulation and cell growth signaling cascades, gets disrupted, it upsets the cell cycle progression. Such cells with unchecked cell cycles start proliferating uncontrollably and eventually develop into tumors.
Such genes that act...
8.8K