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Updated: Jun 26, 2025

A Closed-Type Wireless Nanopore Electrode for Analyzing Single Nanoparticles
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A Closed-Type Wireless Nanopore Electrode for Analyzing Single Nanoparticles

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使用设计的核酸纳米结构载体和纳米孔进行特定的小分子检测

Zhipeng Xie1, Zihao Chen1, Aijia Li1

  • 1The Institute for Advanced Studies, Wuhan University, Wuhan 430072, Hubei, P. R. China.

Analytical chemistry
|May 10, 2024
PubMed
概括

这项研究介绍了一种使用DNA纳米结构检测小分子的新纳米孔传感方法. 该技术提高了灵敏度和信号噪声比,改善了临床诊断.

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Labeling DNA Probes03:31

Labeling DNA Probes

DNA probes are fragments of DNA labeled with a reporter tag to enable their detection or purification. The resulting labeled DNA probes can then hybridize to target nucleic acid sequences through complementary base-pairing, and may be used to recover or identify these regions.
Radioisotopes, fluorophores, or small molecule binding partners like biotin or digoxigenin, are the most widely used reporter tags for labeling DNA probes. These labels can be attached to the probe DNA molecule via...
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