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用DCE-MRI基于压缩感应体积插曲的喘息检查对甲状腺结节的差异诊断:可行性研究

Junhao Huang¹, Daihong Liu¹, Jiao Chen¹

¹Department of Radiology, Chongqing University Cancer Hospital, School of Medicine, Chongqing University, Chongqing, China.

Magnetic resonance imaging

|May 10, 2024

概括

使用CS-VIBE的动态对比增强MRI (DCE-MRI) 有效地区分良性和恶性甲状腺结节. 像Ktrans这样的定量参数显示出高的诊断性能,有助于非侵入性病理类型.

科学领域:

放射学放射学是一门学科.
在瘤学瘤学.
医疗成像医学成像

背景情况:

甲状腺结节很常见,需要准确地区分良性和恶性类型.
非侵入性地区分结节类型对于适当的患者管理至关重要.
动态对比增强型MRI (DCE-MRI) 具有特征组织 perfusion 和血管性的潜力.

研究的目的:

从CS-VIBE DCE-MRI.评估定量和半定量参数的诊断性能.
评估这些参数在甲状腺结节的差异诊断中的有用性.
将DCE-MRI参数的疗效与外科病理学发现进行比较.

主要方法:

有望招募208名患有259例手术确认甲状腺结节的患者.
采用压缩感应体积插入呼吸暂停 (CS-VIBE) 技术获取常规和DCE-MRI.
对量化 (Ktrans,Kep,Ve) 和半量化参数 (洗进,洗出,TTP,AT,PEI,IAUC) 和时间强度曲线 (TIC) 类型的分析.

主要成果:

恶性和良性结节之间的Ktrans,Kep,Ve,洗进,洗出,PEI和iAUC的显著差异 (P < 0.001).
在区分结核类型方面,Ktrans表现出最高的诊断性能 (所有结核的AUC为0.854,FA为0.895,NG为0.609).
第三类TIC曲线在良性结节中更常见 (77.4%),而第二类曲线在恶性结节中更常见 (57.5%).

结论:

基于CS-VIBE的DCE-MRI是一种可行的非侵入性方法,用于甲状腺结节的特征.
定量和半定量DCE-MRI参数可以有效地区分良性和恶性甲状腺结节.
这种成像技术有助于识别甲状腺结节的特定病理类型.

关键词:

在DCE-MRI中,使用的是DCE-MRI.差异诊断是一种差异诊断.运动学运动学甲状腺结节甲状腺结节

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