综合药物管理 (CMM):在瘤血液学中应用一种新的药物实践
Sabah Mansour1, Fatima Zohra Nadjet Mekaouche1, Halima Rouabah1
1Faculty of Medicine of Oran, Oran, Algeria; Pharmacovigilance service, EHU Oran, Oran, Algeria.
Annales pharmaceutiques francaises
|May 10, 2024
概括
临床药剂师驱动的综合药物管理 (CMM) 服务显著减少了瘤血液病患者的药物相关问题 (DRP). 这种干预优化了治疗的管理,防止了伤害,改善了患者的护理.
科学领域:
- 在瘤学瘤学.
- 药理学 药理学是指药理学的学科.
- 临床药房 临床药房
背景情况:
- 由于复杂的药物治疗方案,癌症患者面临更多与药物相关的问题 (DRP).
- 临床药剂师在通过干预来管理这些DRP方面发挥着至关重要的作用.
研究的目的:
- 评估临床药剂师驱动的综合药物管理 (CMM) 服务对瘤血液病患者的影响.
- 评估该患者群体中DRP的发生率和治疗坚持程度.
主要方法:
- 在瘤学和血液学部门进行长达六个月的前性干预研究.
- 使用8项莫里斯基药物坚持量表 (MMAS) 和PCNE分类V9.1进行DRP评估.
- 包括130名瘤血液病患者.
主要成果:
- 确定了879名DRP (平均6.78/患者),其中51%与疗效有关.
- 44.6%的患者表现出治疗坚持不良.
- 卫生专业人员的不适当管理是最常见的DRP原因 (19.9%).
- 提出了875种药物干预措施 (PI),接受率为94.1%.
结论:
- 在瘤血液学中,CMM服务对于优化药物治疗方案和药物管理至关重要.
- 药剂师的干预有效地减少了DRP,并在癌症护理中预防了iatropathology.
- 整合CMM可以改善整体患者管理和安全.
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