相关实验视频

Updated: Jun 26, 2025

Testing Targeted Therapies in Cancer using Structural DNA Alteration Analysis and Patient-Derived Xenografts
10:27

Testing Targeted Therapies in Cancer using Structural DNA Alteration Analysis and Patient-Derived Xenografts

Published on: July 25, 2020

7.2K

老年转移性乳腺癌患者中使用CDK4/6抑制剂治疗的现实世界经验

Thomas N O'Connor1, Emily Schultz1, Jianxin Wang1

  • 1Department of Molecular and Cellular Biology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA.

Cancers
|May 11, 2024
PubMed
概括

接受CDK4/6抑制剂的转移性激素受体阳性乳腺癌的老年人 (≥70) 经历了更长的无进展生存期,但更多的副作用. 建议对剂量调整进行进一步的研究.

关键词:
这是一种CDK4/6抑制剂.乳腺癌 乳腺癌 乳腺癌年长的老人老年人老年人.转移性转移性 转移性

更多相关视频

Evaluating the Effectiveness of Cancer Drug Sensitization In Vitro and In Vivo09:19

Evaluating the Effectiveness of Cancer Drug Sensitization In Vitro and In Vivo

Published on: February 6, 2015

8.7K
Orthotopic Transplantation of Breast Tumors as Preclinical Models for Breast Cancer07:45

Orthotopic Transplantation of Breast Tumors as Preclinical Models for Breast Cancer

Published on: May 18, 2020

6.0K

相关概念视频

Inhibition of Cdk Activity02:34

Inhibition of Cdk Activity

The orderly progression of the cell cycle depends on the activation of Cdk protein by binding to its cyclin partner. However, the cell cycle must be restricted when undergoing abnormal changes. Most cancers correlate to the deregulated cell cycle, and since Cdks are a central component of the cell cycle, Cdk inhibitors are extensively studied to develop anticancer agents. For instance, cyclin D associates with several Cdks, such as Cdk 4/6, to form an active complex. The cyclin D-Cdk4/6 complex...
4.7K