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多发性骨髓瘤患者两个运动干预措施对身体功能的影响:试点可行性研究

Jens Hillengass¹, Michaela Hillengass², Janine M Joseph²

¹Department of Medicine-Myeloma, Roswell Park Comprehensive Cancer Center, Elm and Carlton Streets, Buffalo, NY 14263, USA.

|May 11, 2024

概括

这项研究发现,监督力量训练和家庭散步都是多发性骨髓瘤 (MM) 患者可行的运动干预措施. 与步行相比,力量训练对身体功能有更持久的益处.

科学领域:

在瘤学瘤学.
康复医学康复医学康复医学
运动生理学运动生理学

背景情况:

多发性髓瘤 (MM) 经常导致骨破坏,导致避免炼.
身体活动对于管理MM症状和改善生活质量至关重要.

研究的目的:

对MM患者进行两次6个月的运动干预措施的可行性进行评估.
为了比较家庭散步与监督力量训练对身体功能和疼痛的影响.

主要方法:

一项前性试验涉及42名MM患者,分为步行组 (n=18) 和力量训练组 (n=24).
干预措施包括远程提示的家庭散步或监督的力量训练.
使用多个标准化测试 (AM-PAC,6 MWT,30 SST,TUG,VAS) 评估身体功能和疼痛.

主要成果:

这两种干预都是可行的,没有严重的不良事件;肌肉骨问题是最常见的不良事件.
力量训练组在AM-PAC,TUG,6MWT和30SST中显示出显著的改善,干预后六个月持续效应 (除6MWT外).
步行组在AM-PAC,TUG,6MWT和30SST有所改善,AM-PAC和TUG的持续变化.

结论:

对MM患者来说,监督的力量训练和在家进行的步行干预都是可行的.
六个月的力量训练证明了对身体功能的持续益处,而步行显示出较小,但仍然显著的持续效果.
这些发现支持运动作为多发性骨髓瘤患者护理的可行组成部分,需要在更大规模的试验中进一步调查.

关键词:

多发性骨髓瘤是多发性骨髓瘤的一种.疼痛疼痛疼痛疼痛身体活动身体活动身体功能身体功能身体功能人们的生活质量.

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