用PDLA和PLLA复合膜合成MPEG-b-PLLA双块共聚物及其结晶性能
Wenjing Wu1, Weixin Wu1, Mingwei Guo2
1College of Chemical Engineering, Nanjing Forestry University, Nanjing 210037, China.
Materials (Basel, Switzerland)
|May 11, 2024
概括
甲基聚乙烯甘醇-块聚L-乳酸 (MPEG-b-PLLA) 影响复合膜的结晶性. 最佳结晶发生在PDLA矩阵中,添加3%的MPEG-b-PLLA,由DSC,POM和WAXD证实.
科学领域:
- 聚合物科学 聚合物科学
- 材料科学 材料科学 材料科学
背景情况:
- 甲基聚乙烯糖醇-块聚L-乳化物 (MPEG-b-PLLA) 在药物和生物学中至关重要.
- 它的结构和形态已经很成熟.
- 合成涉及环开放聚合,控制乳酸数量.
研究的目的:
- 研究MPEG-b-PLLA共聚合物及其混合物的热力学和结晶性质.
- 为了分析PDLA/MPEG-b-PLA和PLLA/MPEG-b-PLA复合膜的结晶动力学.
- 为了确定MPEG-b-PLLA内容对混合物晶度的影响.
主要方法:
- 通过环开聚合合成MPEG-b-PLLA的合成.
- 差异扫描热度计 (DSC) 用于结晶运动.
- 极化光学显微镜 (POM) 和广角X射线衍射 (WAXD) 用于结构确认.
主要成果:
- 结晶动力学取决于MPEG-b-PLLA块的添加水平.
- 样品晶度最初上升,然后随着MPEG-b-PLLA含量增加而下降.
- 在PDLA矩阵中观察到3%MPEG-b-PLLA.PLLA的最大结晶性能.
结论:
- MPEG-b-PLLA内容显著影响PDLA和PLLA复合膜的结晶行为.
- 添加MPEG-b-PLLA可以优化,以提高混合晶体性.
- 3%的MPEG-b-PLLA在PDLA矩阵中产生了优越的结晶性质.
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