大规模输血协议和急性腹出血患者的结果
Aryoung Kim1,2, Dong Hyun Sinn1, Byeong Geun Song1
1Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 06351, Republic of Korea.
Journal of clinical medicine
|May 11, 2024
概括
大规模输血协议 (MTP) 与急性水出血 (AVB) 患者的结果更差有关. 这项研究发现,MTP激活显著增加了AVB患者的死亡率和出血控制失败.
科学领域:
- 胃肠病学 胃肠病学
- 肝病学 肝病学是一种肝病学.
- 关键护理医学 关键护理医学
背景情况:
- 大规模输血协议 (MTP) 改善了创伤和一些非创伤性出血休克患者的结果.
- 在急性水出血 (AVB) 中MTP的疗效仍未得到研究.
研究的目的:
- 确定MTP激活对患有急性水出血的患者结果的影响.
- 评估MTP与AVB患者42天死亡率和出血控制之间的关联.
主要方法:
- 从2014年7月到2022年6月连续218名没有恶性瘤的AVB患者的分析.
- 在MTP激活和非MTP组之间对42天死亡率和出血控制失败的比较.
- 倾向性得分匹配用于控制混因素.
主要成果:
- MTP激活与42天死亡率 (42.1%对1.5%) 和出血控制失败 (36.8%对0.5%) 的显著增加有关.
- MTP是42天死亡率的独立预测因素 (HR 21.05-24.04).
- 亚组和倾向分数匹配的分析始终显示MTP组的结果较差.
结论:
- 大规模输血协议的激活与急性水出血患者的不良结果有关.
- 需要进一步的研究来确定MTP是否是大规模AVB病例的可行选择.
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