从诊断到青春期的丸位置的关系下下降的丸增长潜力
Maciej Nowak1, Jerzy Niedzielski1, Jolanta Slowikowska-Hilczer2
1Department of Pediatric Surgery and Urology, University Pediatric Centre, Central University Hospital, Medical University of Lodz, 90-419 Lodz, Poland.
Journal of clinical medicine
|May 11, 2024
概括
没有下降的丸 (UDT) 显示持续增长直到青春期,腹内丸 (IAT) 显示出显著的增长潜力. 丸缩指数 (TAI) 根据UDT类型和年龄组而异,表明追赶增长的潜力.
科学领域:
- 儿科内分泌学 儿科内分泌学
- 安德罗学与人类学
- 发展生物学 发展生物学
背景情况:
- 未下降的丸 (UDT) 是儿科患者常见的一种先天性异常.
- 精确评估丸体积 (TV) 和丸缩指数 (TAI) 对于将UDT分类为正常,低缩或缩至关重要.
- 了解UDT中TV和TAI的动态对于临床管理和预后至关重要.
研究的目的:
- 在24个月的时间内,研究不同类型的未下降丸 (UDT) 的男孩的丸体积 (TV) 和丸缩指数 (TAI) 的变化.
- 建立基于电视和TAI的正常,低缩和缩UDT的标准.
- 评估各种UDT分类和年龄组的丸生长潜力 (TGP).
主要方法:
- 长度研究涉及182名男孩,年龄为0.3-14.0岁,有212名UDT.
- 在24个月间隔进行了两次评估,以跟踪丸参数的变化.
- UDT的分类为单侧阴道 (UCT),双侧阴道 (BCT) 和腹内丸 (IAT).
主要成果:
- 最初的TAI在IAT (38.1%) 中最高,在BCT (12.5%) 中最低. 2年后,TAI在BCT (20.5%) 和IAT (19.1%) 中增加,而在UCT (12.0%) 中下降.
- 较年轻的男孩 (<6岁) 起初 (25.0%) 和随访时 (18.2%) 的TAI高于青春期男孩 (12-14岁) (起初5.9%,随访时7.3%).
- 腹部内丸 (IAT) 显示丸生长潜力最高 (TGP) 为120.0%,而双边状丸 (BCT) 则最低,为28.6%. 在男孩<3岁 (100%) 和12-14岁 (98.1%) 中观察到最高的TGP.
结论:
- 未下降的丸 (UDT) 在整个童年和青春期都表现出持续的增长,不管它们的解剖位置如何.
- 腹内丸 (IAT) 具有显著的生长潜力,这表明体积恢复的预后有利.
- 该研究为UDT的自然历史提供了宝贵的见解,有助于制定有针对性的管理策略.
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