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计算机断层扫描的低骨矿物质密度:经过过导管大动脉置换后与生存率差的关联

Caglayan Demirel¹, Kseniya Halavina¹, Kevin Hamzaraj¹

¹Department of Internal Medicine II, Clinical Division of Cardiology, Medical University of Vienna, 1090 Vienna, Austria.

Journal of clinical medicine

|May 11, 2024

概括

通过导管大动脉置换 (TAVR) 计算机断层扫描 (CT) 检测到的低骨矿物质密度 (BMD) 与患者的长期存活率降低有关. 这一发现表明,常规的TAVR-CT可以帮助评估TAVR接受者的脆弱性和改善风险预测.

科学领域:

心脏病学心脏病学
放射学放射学是一门学科.
老年病的医生老年病的医生

背景情况:

过导管大动脉置换 (TAVR) 是严重的大动脉狭窄症 (AS) 的首要治疗方法.
术前计算机断层扫描 (CT) 对于TAVR规划至关重要.
脑电图扫描也可能揭示骨矿物质密度 (BMD),骨脆弱的指标,但其在TAVR患者的预后价值是不清楚的.

研究的目的:

使用常规TAVR-CT扫描来评估骨矿物质密度 (BMD).
确定BMD对TAVR患者长期生存的影响.

主要方法:

对770名TAVR患者 (2015年11月 - 2022年3月) 的回顾性分析.
在不增强的CT扫描中,从胸椎水平的单个轴图像上测量BMD.
考克斯回归和限制立方线模型被用于分析BMD与死亡率的关联.

主要成果:

平均 BMD 是 147.5 ± 5.4 霍恩斯菲尔德单位 (HU).
较低的BMD与死亡率的增加显著相关 (调整后HR每100个HU下降:1.27;p=0.041).
骨质量低于200HU表明死亡风险大幅增加.

结论:

在TAVR-CT上低的BMD是降低存活率的独立预测因素.
TAVR-CT可以作为评估脆弱性的宝贵工具.
纳入BMD评估可能会提高TAVR患者的风险预测.

关键词:

大动脉门狭窄症骨矿物质密度骨矿物质密度计算机断层扫描 (CT) 是一种计算机断层扫描.死亡率死亡率

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