来自高产乳牛群的未接种疫苗的奶牛中主要呼吸道病毒的血清分析
Geovana Depieri Yoshitani1, Stefany Lia Oliveira Camilo2, Juliana Torres Tomazi Fritzen1
1Laboratory of Animal Virology, Department of Veterinary Preventive Medicine, Universidade Estadual de Londrina, Londrina 86057-970, PR, Brazil.
Animals : an open access journal from MDPI
|May 11, 2024
概括
巴西的高产奶牛广泛暴露于牛呼吸系统疾病病毒,包括牛αherpesvirus1和牛病毒性腹病毒. 建议在牛群中进行疫苗接种以预防BRD.
科学领域:
- 兽医病毒学 兽医病毒学
- 动物卫生 动物健康
- 流行病学 流行病学
背景情况:
- 牛呼吸道疾病 (BRD) 在全球范围内对牛群构成重大威胁.
- 了解关键的BRD相关病毒的血清流行率对于有效的疾病管理至关重要.
- 高产的奶牛特别容易感染呼吸道感染.
研究的目的:
- 为了确定奶牛的血清状况四个主要的BRD病毒:牛的alphaherpesvirus1 (BoAHV1),牛的病毒性腹病毒 (BVDV),牛的偏流感病毒3 (BPIV3),和牛呼吸道同胞性病毒 (BRSV).
- 为了评估这些病毒在巴西帕拉纳州未接种疫苗的乳牛群中本土传播的情况.
- 提供支持实施针对性疫苗接种策略的数据,以预防BRD.
主要方法:
- 从39只未接种疫苗的奶牛群中采集了497个血清样本,这些奶牛没有呼吸系统疾病的临床症状.
- 使用病毒中和 (VN) 试验进行血清分析,检测针对BoAHV1,BVDV,BPIV3和BRSV的抗体.
- 统计分析单个奶牛和群体水平上的血清阳性率.
主要成果:
- 在所有四种病毒中都观察到高血清流行率:BPIV3 (96.8%),BoAHV1 (71.4%),BRSV (63.4%) 和BVDV (56.3%).
- 所有39个群体的测试结果为BPIV3呈阳性,对BVDV (82.0%),BRSV (84.6%) 和BoAHV1 (79.5%) 的高群体水平血清阳性.
- 血清阳性因群体管理实践和群体大小而异,这表明病毒在当地流行.
结论:
- 该研究证实了巴西帕拉纳州乳牛群中BoAHV1,BVDV,BPIV3和BRSV的特有存在.
- 在未接种疫苗的动物中高血清流行率强调了需要采取积极的疾病控制措施.
- 建议实施牛的疫苗接种计划,以赋予小牛的被动免疫力和母牛的活性免疫力,以帮助预防BRD.
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