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在人类癌症中增强TP53突变独立设置中的亡

Nicola Di-Iacovo1, Simona Ferracchiato1, Stefania Pieroni1

  • 1Section of General Pathology, Department of Medicine and Surgery, University of Perugia, 06129 Perugia, Italy.

International journal of molecular sciences
|May 11, 2024
PubMed
概括

类似于乌比奎丁的蛋白HOPS/TMUB1调节p53突变的活性,诱导癌细胞的亡. 这突出了HOPS/TMUB1作为超出TP53突变的潜在治疗点.

关键词:
在HOPS/TMUB1中使用.在TCGA数据中,TCGA数据为:灭症 (apoptosis) 是一种死亡的过程.乳腺癌 乳腺癌 乳腺癌功能的增益 (GOF)肺癌是一种肺癌.在 p53 里,p53 是一个 p53 的类型.胰腺癌是一种癌症.

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