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Updated: Jun 26, 2025

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基因表达特征对未折叠蛋白质反应作为类风湿性关节炎患者的风险调节器

Aleksandra Kucharska-Lusina1, Maciej Skrzypek1, Aleksandra Binda1

  • 1Department of Clinical Chemistry and Biochemistry, Medical University of Lodz, 92-215 Lodz, Poland.

International journal of molecular sciences
|May 11, 2024
PubMed
概括

慢性内质网膜 (ER) 压力,由PERK和ATF4等UPR基因的mRNA翻译增加表明,与类风湿性关节炎 (RA) 有关. 针对PERK途径可能提供新的RA治疗策略.

关键词:
一些ER-adaptosome可以适应.这是一种PERK抑制剂.细胞内膜网膜的压力应激类风湿性关节炎 类风湿性关节炎不折叠的蛋白质反应反应

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